Technology

Sidero owns the patented Medical Food technology platform, Siderosorb™, utilizing Baker’s Yeast, Saccharomyces cerevisiae, to deliver therapeutic proteins/complexes directly to the GI tract in order to ameliorate human disease. Medical foods have a simplified and streamlined regulatory pathway allowing rapid and low-cost development, significantly accelerating market access and are routinely covered by medical insurance.  Nutritional yeast contains all nine essential amino acids and is consumed by most world cultures, most popular as the Australian Vegemite, demonstrating that our delivery mechanism is generally regarded as safe, affordable, and in a readily acceptable form.

Siderosorb™ Technology


Overview
Saccharomyces cerevisiae has been used for over 9,000 years to make leavened bread, ferment alcoholic beverages, and as an excellent nutritional source. It is even the official state microbe of Oregon.


Yeast is a microbe that is also widely used as a molecular genetic research tool based on its many attributes including:


  • S. cerevisiae is a microbe that replicates very quickly (about 90 min/cell division)
  • It is eukaryotic with cellular physiology more similar to mammals than to bacteria
  • Its genome has been completely sequenced
  • A majority of yeast genes have human similarities
  • ​Its genome is readily manipulated, including insertion of human genes for expression
  • It can grow in either a haploid or diploid state expanding its genetic manipulation capabilities
  • S. cerevisiae is not pathogenic
  • Nutritional yeast is consumed by most cultures around the world